ISSN 0187-893X       ISSNE 1870-8404
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Guide authors of the current issue Volumen XXVIII, Número 1, January de 2017 Volumen XXVII, Número 4, October de 2016 Volumen XXVII, Número 3, July de 2016 Volumen XXVII, Número 2, April de 2016
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Number 2,

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Number 1











,    2 - 10
Science has been taught and understood by students as a result of events in linear time, successive and interrelated. This way of thinking about the scientific work has led to the misunderstanding of the nature of science. To contribute to combat this distortion in the perception ofscience, this study aims to report a literature review on the concepts of acids and bases, starting from the analysis of the progress of these theories in history, especially in the nineteenth and twentieth century. The progress of these theories is represented by means of a chronological map that interrelates the scientific research lines of the main researchers that have developed theories that area. The chronological map aims to be an effective teaching tool to illustrate the evolution of science in the development of acid-base theories. It may be used in the classroom by allowing students to understand the connections of scientific theories and analyze the profile of developments in scientific work.

Propiedades del triioduro de antimonio fotodescomposición y acidez de Lewis

, ,    11 - 13
Antimony triiodide is aversatile compound that is not studied in detail in the current Inorganic Chemistry literature at the undergraduate level. In this work we propose a simple microscale synthesis describing two other interesting properties which are not reported in the common chemical literature: photo-oxidation and acid---base reaction in non-aqueous media. Theexperimentcanbesuccessfullyandsafelyachievedinatwo-hourlabclassatthesophomore level.


Usefulness of the Chemistry according to Mechanical Engineering students: Effect of a teaching proposal

, ,    14 - 21
An investigation about usefulness of chemistry in engineering students formation according to their perception is shown. In particular, it is intended to discover how useful ChemistryisforfirstyearBachelorofMechanicalEngineeringstudentsandhowtohelpstudents improve their views on the usefulness of chemistry. It has carried out a teaching proposal into 2 groups and then, the results were compared with another group, which has not been done this teaching proposal. The assessments and justifications of the students about the usefulness of chemistry were obtained at the beginning and end of the course, through a task that should be noted in a Likert scale of 1 to 4 and an open question to give reasons for its assessment. It was found differences in the assessment of the usefulness of chemistry between the groups which have participated in the teaching proposal and another one, which has not participated in it. It alsofoundastrongagreementbetweenratingsonaLikertscaleandjustificationsprovided.The results support the teaching proposal, showing the importance of the usefulness of chemistry for their training and professional future, although it is considered necessary to further this line.

Using Avogadro as molecular editor for Odontology first year students in a course of General and Organic Chemistry

, , ,    22 - 29
Today, molecular viewers are an undeniable reality in the classroom. This type of softwares allow students the 3 dimensional development. In this study, free access molecular viewer Avogadro was used. The using of the program was successful not only in the 3 dimensional training, but in the pointing out of carbons’ quilarity of optical isomers. In fact, the velocity was reduced to a half part in comparison to bidimensional molecules. On the other hand, students were prone to the usage of Avogadro in basic and advanced chemical courses.


Analysis of the perceptions of students on the flipped classroom methodology for teaching advanced techniques in analysis laboratories of residues of veterinary drugs and contaminants

,    30 - 37
Wepresentanexperienceinwhichweanalyzetheperceptionsofstudentsaboutthe flipped classroom methodology for teaching on advanced techniques in laboratories of residues ofveterinarydrugsandcontaminants.Itwasconductedwith31participants,professionalsfrom different areas, in a professional qualification course for laboratory technicians in Spain unde the model flipped classrooms. We analyze the feedback from participants on the usefulness of the resources used and the methodology followed. The results show that conceptions of participants on learning influence on assessment and acceptance of this methodology.

Pulmonary tuberculosis: The global epidemic continues and the teaching of this topic is crucial and complex

, ,    38 - 43
Understanding of tuberculosis (TB) requires students to identify some critical points. The disease is caused by Mycobacterium tuberculosis, a peculiar bacterium mainly transmitted by inhaling infectious droplets expelled when coughing, talking and sneezing. One of the least understood aspects is that, following the exposure to the infectious droplets, a third of the people develop a latent pulmonary infection. The last means that some people control, rather than eliminate, the bacteria; therefore, some of them can later develop the TB disease, especiallywhentheypresentanimmunologicaldeficiency.Thekeyistorecognizethecell-mediated immunity as a determining factor in the course of the latent or active infection and that the antibodies, the complement system and the phagocytosis by non-activated macrophages result irrelevant in the defense against TB. Another major concern is the effect of multidrug resistant and extensively drug resistant strains. Management of multidrug resistant -TB and extensively drug resistant -TB is more complicated due the long treatment periods and the elevated costs.

N-arylation of the imidazole via Cul: A tutorial for optimization of a catalytic system through of experimental design

, ,    44 - 50
This work deals the development of a catalytic system for the N-arylation of imidazole with CuI through experimental design. 1,10-Phenanthroline (bidentate ligand) was used and proved to be efficient in the coupling of iodo- and bromoarenes with imidazole. Thus, the article presented here is intended to serve as a tutorial for optimization of new catalytic systems and may be applied as a low-cost practical class for chemistry undergraduate students.

Drug discovery and development: A computational approach

, ,    51 - 58
Drug discovery is a complex and expensive process where different research areas converge. Computational methods have been part of the multidisciplinary efforts and their principles should be included in courses of Medicinal Chemistry. In a given project, the application of computational approaches depends on the information available for the system and the specific goals of the study. Computational approaches have made key contributions to perform efficient analyses of data, filtering compounds collections to select molecules for experimental screening, generate hypothesis to understand the mechanism of action of drugs, and the design of new chemical structures. In addition, computational methods have made significant contributions to develop drugs that are in clinical use. However, there are several challenges to face. Addressing these challenges promote innovation and improvement of methodologies that form part of the multidisciplinary effort to develop drugs.

The advantages of being weak: Nobel Prize in Chemistry 2016

   59 - 61
The Nobel Prize in Chemistry 2016 was awarded to Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa ‘for the design and synthesis of molecular machines’. To understand molecular machines it is important to know about supramolecular chemistry, that was developed by Donald J. Cram, Jean-Marie Lehn and Charles J. Pedersen, also Nobel Prize winners in 1987. For molecular machines, the main issue is the bond between molecules that is very weak. In this paper, a brief description of the molecular machines is presented.


Commenting on the Nobel... «in the dark and with box gloves»

   62 - 63
This is an example of how to use the subject in the classroom to develop or reinforce students’ knowledge of intermolecular forces, their origin and their consequences on the properties of materials.